From: Chicago

Take I90W to Portage, north of Madison.
Take I39/US-51 north to Hurley.
Take US-2 east to Indianhead. 375 miles (approx. 6-8 hours)

From: Green Bay

Take 47 west to US-45 north of Antigo.
Take US-45 north to Watersmeet, MI.
Take US-2 west to Indianhead. 215 miles (approx. 4 hours)

From: Madison

Take I90 north to Portage.
Take I39/US-51 north to Hurley.
Take US-2 east to Indianhead. 285 miles (approx. 4-5 hours)

From: Milwaukee

Take US-41 north to Oshkosh.
Take 110 west to US-10, continue west to Stevens Point.
Take US-51 north to Hurley.
Take US-2 east to Indianhead. 320 miles (approx. 5-7 hours)

From: Minneapolis

Take I35 north to Duluth.
Take US-2 east to Indianhead. 225 miles (approx. 4.5 hours)

From: St. Paul

Take I94 east to US-63(Baldwin).
Take US-63 to US-2, west of Ashland.
Take US-2 east to Indianhead. 225 miles (approx. 4.5 hours)